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Administrative Procedure Act (APA): Federal law governing how administrative agencies propose and establish regulations, including procedural requirements for agency actions.

Federal Grant and Cooperative Agreement Act: Establishes criteria for choosing appropriate legal instruments to use in federal assistance transactions, including MOUs.

Freedom of Information Act (FOIA): Requires disclosure of government documents and information, which may affect how the MOU's content is handled and disclosed.

Privacy Act of 1974: Governs the collection, maintenance, use, and dissemination of personal information maintained by federal agencies.

Anti-Deficiency Act: Prohibits federal agencies from obligating or expending federal funds in advance or in excess of an appropriation.

Federal Acquisition Regulation (FAR): Primary regulation for use by federal agencies in their acquisition of supplies and services with appropriated funds.

Agency-Specific Regulations: Internal policies, statutory authority, and delegation requirements specific to the federal agency involved in the MOU.

Purpose Statute: Requires that appropriated funds be used only for their intended purpose as specified in the appropriation.

Time Statute: Governs the time period during which appropriated funds must be used.

Amount Statute: Controls the amount of funds that can be obligated or expended by federal agencies.

Economy Act: Allows federal agencies to purchase goods or services from other federal agencies or to obtain specialized services.

Intergovernmental Cooperation Act: Enables federal, state, and local governments to work together efficiently through agreements and shared resources.

Standards of Ethical Conduct: Regulations governing the ethical behavior and responsibilities of government employees involved in the MOU process.

State Administrative Procedures: State-specific requirements for administrative actions and intergovernmental agreements when state agencies are involved.

Constitutional Framework: Fundamental principles including separation of powers, federalism, and spending clause limitations affecting intergovernmental agreements.